|
KMID : 0390119960360010045
|
|
Journal of Pusan Medical College
1996 Volume.36 No. 1 p.45 ~ p.52
|
|
|
Effect of Ionic and Non-ionic Contrast Media on Blood Coagulation
|
|
|
|
|
Abstract
|
|
|
It has been reported that newly developed non-ionic contrast media is less effective in anti-coagulation than contrast media. In the present study, anti-coagulation properties were evaluated in vitro and effect on blood coagulation in vivo were
also
evaluated. The contrast media used were Iothalamate (high osmolar ionic contrast media) and Isopamiro 370 (non-ionic contrast media).
@ES 1. In vivo study
The results showed very significant difference in anti-coagulation effect between the ionic group and the non-ionic group (p<0.05). Clotting time in non-inonic contrast media group was shorter in 30% concentration than that of ionic contrast
media.
Non-ionic contrast media has anti-coagulation effect, but less effective than ionie contrast media.
@ES 2. In vivo study
@EN Before injection of the contrast media, the bleeding time and coagulation time were within normal. After 30 minutes injection of the contrast media, the bleeding and coagulation time were also within normal limit. This results showed no
difference
in anti-coagulation effect between the ionic contrast media and non-ionic contrast media.
Based on these results it is concluded that non-ionic contrast media was less effective in anti-coagulation than ionic contrast media in vitro but both ionic and non-ionic contrast media had little effect on blood coagulation in vivo.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|